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What did they do? (Methods) |
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1. Were patients randomized? |
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2. Was randomization concealed? |
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3. Were patients analyzed in the groups to which they were
randomized? |
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4. Were patients in the treatment and control groups similar
with respect to known prognostic factors? |
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5. Were 5 important groups (patients, caregivers, collectors of
outcome data, adjudicators of outcome, data analysts) aware of group
allocation? |
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6. Aside from the experimental intervention, were the groups
treated equally? |
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7. Was follow-up complete? |
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What was the answer? (Results) |
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1. How large was the treatment effect? |
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2. How precise was the estimate of the treatment effect?
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What did they say about the answer?
(Conclusion) |
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1. Do the results of the study support the author/s
conclusions? |
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2. Does the conclusion reflect the discussion? |
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3. Are there study limitations, and do these impact the
conclusions? |
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4. Are potential discrepancies mentioned? |
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What do I do with this information? |
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1. Were the study patients similar to my patients? |
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2. Were all patient important outcomes considered? |
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3. Are the likely benefits worth the potential harms and costs?
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