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Diagnostic and Clinical Support Tools

Diagnostic and clinical support resources can help clinicians and learners investigate symptoms, develop differential diagnoses, review diagnostic criteria, evaluate testing options, and locate evidence-based information at the point of care.

These tools support different parts of the diagnostic process. Some generate or refine differential diagnoses, while others provide evidence summaries, diagnostic criteria, clinical images, examination techniques, or authoritative reference information.

These resources are intended to support, not replace, clinical reasoning and professional judgment.

Not sure which resource to use? See Which resource should I use?

Clinical Decision Support

ClinicalKey AI
An AI-assisted clinical information and decision-support tool grounded in Elsevier medical content. ClinicalKey AI can help clinicians investigate complex clinical questions, generate and refine differential diagnoses, summarize evidence, and explore diagnostic and management considerations.

Responses include supporting references so users can review the underlying clinical information and evidence.

ClinicalKey AI App Information

DynaMedex
Point-of-care clinical information combining evidence-based disease and condition information with drug information. Topics include diagnostic evaluation, differential diagnosis, treatment, prognosis, prevention, and other information needed for clinical decision-making.

ClinicalKey
Clinical search and reference resource providing books, journals, clinical overviews, guidelines, images, videos, drug information, and other clinical content. Useful for investigating diseases and conditions and reviewing diagnosis, treatment, and management information.

Differential Diagnosis Tools

Diagnosaurus
via AccessMedicine
A quick-reference differential diagnosis tool for exploring possible diagnoses associated with symptoms, signs, and diseases. Entries can also be browsed by organ system.

Isabel
integrated with DynaMedex
Clinical decision support tool that generates a differential diagnosis from patient findings. Isabel can help broaden diagnostic considerations and identify possible diagnoses for further investigation.

For additional resources specifically focused on developing a differential diagnosis, see Differential Diagnosis Resources .

Visual Diagnosis

VisualDx + DermExpert
Clinical decision support resource combining an extensive medical image collection with tools for building and refining a differential diagnosis. VisualDx is particularly useful for dermatologic and other visually identifiable conditions.

DermExpert is an AI-enabled feature that analyzes photographs of skin findings to assist with lesion characterization and development of a differential diagnosis. Clinical findings can be added to refine the results.

MUSM Preceptors/Affiliates without a Mercer email: Please contact Carolyn Klatt for VisualDx login/access information.

Diagnostic Criteria

Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR)
The American Psychiatric Association's authoritative reference for the classification and diagnosis of mental disorders. Includes diagnostic criteria, descriptive text, and related clinical information.

Clinical Examination & Skills

JoVE Clinical Skills
Video demonstrations of clinical skills and examination techniques. Content includes physical examination, emergency medicine and critical care, nursing, and other clinical procedures.

Clinical skills videos can be useful for reviewing examination techniques associated with the collection of diagnostic information and patient assessment.

Which resource should I use?
If you want to... Try...
Ask a complex clinical question and review evidence-supported answers ClinicalKey AI
Find concise evidence-based information at the point of care DynaMedex
Research a disease, diagnosis, or treatment in greater depth ClinicalKey
Generate a differential diagnosis from patient findings Isabel or ClinicalKey AI
Quickly look up a differential for a symptom, sign, or disease Diagnosaurus
Evaluate a skin or visually identifiable condition VisualDx + DermExpert
Review diagnostic criteria for mental disorders DSM-5-TR
Review physical examination or clinical skills techniques JoVE Clinical Skills
Using AI-Enabled Clinical Tools

AI-enabled tools can help clinicians organize complex information, broaden diagnostic considerations, and locate relevant evidence. Their output should be interpreted in the context of the complete clinical picture.

Review supporting evidence, consider important diagnoses that may have been omitted, and confirm clinically significant information using authoritative sources and professional judgment.

For additional information, see AI Tools to Support Clinical Reasoning & Diagnosis .

Need help choosing a clinical resource? MUSM librarians can help you identify clinical decision support tools and evidence-based resources appropriate for your question.

Contact your MUSM Library Liaison

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